Where and how your great-great-great-grandmother lived, say 5000 years ago, is linked to whether and what will you suffer, scientists found. They can now decide what will suffer by a "record" in the DNA in the drafting of which are involved all the generations before us.
"Record" relies on special DNA testing. Everyone has such a record, but the specifics differ. Depending on them geneticists distribute people into groups. They are called Haplogroups, that have subgroups.
In some Haplogroup certain diseases occur more frequently than in others, established scientists. So far they have only hypotheses as to what exactly the mechanism behind the link to a particular haplogroup’s disease ranges.
Each of us belongs to a haplogroup, depending on the specific mutations that our history brings. Mutation does not necessarily mean disease. Some are actually harmful, but others give a survival advantage.
Some mutations are inherited only from the mother and others - only the father. So each of us belongs to 2 haplogroups - one maternal, the other - the father. Mutations that we inherit from our mothers are in mitochondrial DNA, and those of our fathers - in the nuclear DNA.
Until recently, it was believed that all hereditary diseases are work-related genes. If a person inherits a gene that causes disease on both lines - the mother and the father, the disease develops. This is true, but only for certain diseases that are inherited.
But in many cases, the genes have no guilt. The cause of hereditary diseases is beyond them. Genes occupy a very small part of DNA. The rest - 99% is outside influences. Until recently, it was called offensive DNA.
But scientists found that it also is influenced by genes from the effects of environment and under pressure of external factors that tolerate mutations. They go into the offspring, because all DNA is inherited, not just genes.
Knowing what haplogroup we fall into, we can predict what diseases we are at risk of. If you are in the group, with whose representatives most often occurs alcoholism, we can stop drinking, not to pull the devil by the tail.
If you are in the haplogroup, which most often suffers from lung cancer, we can not smoke, not to facilitate additional cancer.
But scientists have yet to ascertain whether the "belonging to haplogroup-risk of disease" calculation is completely accurate.See more